Model NO.: CAS: 61-12-1 Customized: Non-Customized Suitable for: Elderly, Children, Adult Purity: >99% Mf: C20h30cln3o2 Melting Point: 81-82c Trademark: DAHUA Specification: USP/BP HS Code: 3001200020 Powder: Yes Certification: USP State: Powder CAS No: 61-12-1 MW: 379.92 Appearance:
White Powder Transport Package: Foil Bag or According to Your Requirement Origin: Hubei, China 99% Pharmaceutical Intermediates Dibucaine Hydrochloride CAS 61-12-1
1. Quick Details:
Dibucaine hydrochloride CAS: 61-12-1
Dibucaine hydrochloride MF: C20H30ClN3O2
Dibucaine hydrochloride MW: 379.92
Dibucaine hydrochloride EINECS: 200-498-1
Dibucaine hydrochloride Product Categories: Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Dibucaine hydrochloride Chemical Properties: white powder
Dibucaine hydrochloride Usage Anesthetic (local).
| Test Items | Specification | Test Results |
| Description | White or almost white crystalline powder | White crystalline powder |
| Melting Point | 191.0~193.0ºC | 192ºC |
| Loss of drying | ≤1.0% | 0.5% |
| Heavy Metal | ≤20ppm | 15ppm |
| TLC | Only one spot | Only one spot |
| Assay | ≥99.5% | 99.91% |
| Conclusion | It complies with the USP 32. |
Description:
Dibucaine hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting
Local Anesthetics and its parenteral use is restricted. The drug blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.
In combination sodium dibucaine hydrochloride is administered to dogs to induce rapid, humane, painless euthanasia. The euthanasia solution is toxic to wildlife. Euthanized animals must be properly disposed of by deep burial, incineration or other method in compliance with state and local laws
Applications:
Spinal anesthesia (high, low, saddle block) and topically to produce surface anesthesia. Eye: To anesthetize conjunctiva and cornea prior to superficial procedures (including tonometry, gonioscopy, removal of foreign bodies or sutures, corneal scraping).
Nose and Throat: To abolish laryngeal and esophageal reflexes prior to bronchoscopy, esophagoscopy.
Skin: To relieve pruritus, pain, burning.
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